Skip to main content

O positive blood type

What O+ means for antigens, compatibility and inheritance

What O positive (O+) blood means: no A or B antigens with RhD present, who O+ can donate red cells to, who it can receive from, plasma notes, and inheritance context.

Quick answer

O positive (O+) means red blood cells carry neither the A nor B antigen but do carry the RhD antigen. O+ red cells can generally be given to O+, A+, B+, and AB+ recipients, and O+ people can generally receive red cells only from O+ and O− donors.

What O+ means

O indicates no A or B antigens on red cells. Plasma from type O people typically contains both anti-A and anti-B antibodies, which is why O recipients can only receive type O red cells.

The plus sign indicates the RhD antigen is present, so O+ recipients can receive either Rh-positive or Rh-negative red cells.

O positive is the most common blood type in many populations and is heavily relied on by blood services for Rh-positive recipients.

O positive at a glance
PropertyValue
ABO groupO
Rh (D) statusPositive (RhD antigen present)
Red cell antigensRhD
Plasma antibodies (typical)anti-A, anti-B

Compatibility summary

General red cell and plasma compatibility for O+ under the simplified ABO/Rh model. Real transfusions also depend on antibody screening and crossmatching.

General compatibility for O+
ProductCan give toCan receive from
Red blood cellsO+, A+, B+, AB+O−, O+
Plasma (ABO only)OA, B, AB, O

See the full compatibility chart for all eight types.

Inheritance context

Type O has only the OO genotype under the standard model. Each parent must have contributed an O allele, so parents may be type A (AO), B (BO), or O (OO), but not AB.

Rh-positive status can be DD or Dd.

Two type O parents are expected to have only type O children under the standard model.

Work through specific parent combinations with the baby blood type calculator, or find which parent types could produce a O+ child with the parent calculator.

Limitations

  • Blood type can only be confirmed by laboratory testing. Family history, calculators, and self-report are not substitutes.
  • Compatibility rules on this page are general educational summaries. Real transfusion decisions also depend on antibody screening, crossmatching, product type, and clinical judgment.
  • Rare variants such as the Bombay phenotype, cis-AB, and weak or partial D expression can produce results that differ from the simplified ABO/Rh model.

Frequently asked questions

Who can O+ donate red blood cells to?
Under general compatibility rules, O+ red cells can be given to: O+, A+, B+, AB+.
Who can O+ receive red blood cells from?
Under general compatibility rules, O+ recipients can receive red cells from: O−, O+.
Is O+ rare?
O+ is one of the more common blood types in most populations, which generally makes compatible blood easier to source.

Try O+ in our tools

Sources

Information on this page is paraphrased from the following authoritative sources.

  1. Facts About Blood and Blood Types(opens in a new tab)American Red Cross
  2. Blood typing(opens in a new tab)MedlinePlus, U.S. National Library of Medicine
  3. Rh Incompatibility(opens in a new tab)MedlinePlus, U.S. National Library of Medicine