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A positive blood type

What A+ means for antigens, compatibility and inheritance

What A positive (A+) blood means: the A antigen, Rh-positive status, who A+ can donate red cells to, who it can receive from, plasma notes, and inheritance context.

By BloodTypeCalc.com Editorial TeamPublished Suggest a correction

Quick answer

A positive (A+) means red blood cells carry the A antigen and the RhD antigen. A+ red cells can generally be given to A+ and AB+ recipients, and A+ people can generally receive red cells from A+, A−, O+, and O− donors.

What A+ means

The letter A indicates that red cells display the A antigen on their surface and that the plasma typically contains anti-B antibodies. The plus sign indicates the RhD antigen is present.

Because A+ people have anti-B antibodies, they should not receive red cells carrying the B antigen (types B and AB). Because they are Rh-positive, they can receive either Rh-positive or Rh-negative red cells.

A positive is one of the more common blood types in many populations, which generally makes compatible red cells easier to source for A+ recipients.

A positive at a glance
PropertyValue
ABO groupA
Rh (D) statusPositive (RhD antigen present)
Red cell antigensA, RhD
Plasma antibodies (typical)anti-B

Compatibility summary

General red cell and plasma compatibility for A+ under the simplified ABO/Rh model. Real transfusions also depend on antibody screening and crossmatching.

General compatibility for A+
ProductCan give toCan receive from
Red blood cellsA+, AB+O−, O+, A−, A+
Plasma (ABO only)A, OA, AB

See the full compatibility chart for all eight types.

Inheritance context

A person with type A blood may have inherited two A alleles (AA) or one A allele and one O allele (AO). The A allele is dominant over O, so both genotypes appear as type A.

Rh-positive status can come from two D alleles (DD) or one D and one d (Dd). Two Rh-positive parents can therefore still have an Rh-negative child if both carry a d allele.

Two type A parents can have type A or type O children under the standard model, but not type B or AB.

Work through specific parent combinations with the baby blood type calculator, or find which parent types could produce a A+ child with the parent calculator.

Limitations

  • Blood type can only be confirmed by laboratory testing. Family history, calculators, and self-report are not substitutes.
  • Compatibility rules on this page are general educational summaries. Real transfusion decisions also depend on antibody screening, crossmatching, product type, and clinical judgment.
  • Rare variants such as the Bombay phenotype, cis-AB, and weak or partial D expression can produce results that differ from the simplified ABO/Rh model.

Frequently asked questions

Who can A+ donate red blood cells to?
Under general compatibility rules, A+ red cells can be given to: A+, AB+.
Who can A+ receive red blood cells from?
Under general compatibility rules, A+ recipients can receive red cells from: O−, O+, A−, A+.
Is A+ rare?
A+ is one of the more common blood types in most populations, which generally makes compatible blood easier to source.

Sources

Information on this page is paraphrased from the following authoritative sources.

  1. Facts About Blood and Blood Types(opens in a new tab)American Red Cross
  2. Blood typing(opens in a new tab)MedlinePlus, U.S. National Library of Medicine
  3. Rh Incompatibility(opens in a new tab)MedlinePlus, U.S. National Library of Medicine