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A positive blood type

What A+ means for antigens, compatibility and inheritance

What A positive (A+) blood means: the A antigen, Rh-positive status, who A+ can donate red cells to, who it can receive from, plasma notes, and inheritance context.

Quick answer

A positive (A+) means red blood cells carry the A antigen and the RhD antigen. A+ red cells can generally be given to A+ and AB+ recipients, and A+ people can generally receive red cells from A+, A−, O+, and O− donors.

What A+ means

The letter A indicates that red cells display the A antigen on their surface and that the plasma typically contains anti-B antibodies. The plus sign indicates the RhD antigen is present.

Because A+ people have anti-B antibodies, they should not receive red cells carrying the B antigen (types B and AB). Because they are Rh-positive, they can receive either Rh-positive or Rh-negative red cells.

A positive is one of the more common blood types in many populations, which generally makes compatible red cells easier to source for A+ recipients.

A positive at a glance
PropertyValue
ABO groupA
Rh (D) statusPositive (RhD antigen present)
Red cell antigensA, RhD
Plasma antibodies (typical)anti-B

Compatibility summary

General red cell and plasma compatibility for A+ under the simplified ABO/Rh model. Real transfusions also depend on antibody screening and crossmatching.

General compatibility for A+
ProductCan give toCan receive from
Red blood cellsA+, AB+O−, O+, A−, A+
Plasma (ABO only)A, OA, AB

See the full compatibility chart for all eight types.

Inheritance context

A person with type A blood may have inherited two A alleles (AA) or one A allele and one O allele (AO). The A allele is dominant over O, so both genotypes appear as type A.

Rh-positive status can come from two D alleles (DD) or one D and one d (Dd). Two Rh-positive parents can therefore still have an Rh-negative child if both carry a d allele.

Two type A parents can have type A or type O children under the standard model, but not type B or AB.

Work through specific parent combinations with the baby blood type calculator, or find which parent types could produce a A+ child with the parent calculator.

Limitations

  • Blood type can only be confirmed by laboratory testing. Family history, calculators, and self-report are not substitutes.
  • Compatibility rules on this page are general educational summaries. Real transfusion decisions also depend on antibody screening, crossmatching, product type, and clinical judgment.
  • Rare variants such as the Bombay phenotype, cis-AB, and weak or partial D expression can produce results that differ from the simplified ABO/Rh model.

Frequently asked questions

Who can A+ donate red blood cells to?
Under general compatibility rules, A+ red cells can be given to: A+, AB+.
Who can A+ receive red blood cells from?
Under general compatibility rules, A+ recipients can receive red cells from: O−, O+, A−, A+.
Is A+ rare?
A+ is one of the more common blood types in most populations, which generally makes compatible blood easier to source.

Try A+ in our tools

Sources

Information on this page is paraphrased from the following authoritative sources.

  1. Facts About Blood and Blood Types(opens in a new tab)American Red Cross
  2. Blood typing(opens in a new tab)MedlinePlus, U.S. National Library of Medicine
  3. Rh Incompatibility(opens in a new tab)MedlinePlus, U.S. National Library of Medicine